Your primary care doctor should always know what medications you’re taking, including ED pills prescribed by another provider. There are many safe, reliable online services offering ED prescriptions. Some may find that Cialis works in two hours and takes the medicine two hours before sexual activity. Cialis can be taken with or without food. According to the FDA, generic medications contain the same active ingredients as brand names, meaning there’s no difference in effectiveness or safety. We considered cost, medications available, and whether generic versions were offered to help reduce costs. The medication was developed by U.Extra 15% off $30 sitewide with code SAVE15; Clip your mystery deal! BOGO 50% off select Walgreens health & wellness. AdComplete the Online Consultation with our Doctor. Personalize Your Needs. If Appropriate, Get a Prescription for ED from RexMD®. Free Shipping AvailableReal Doctors · Free Shipping · Personalized Plan · Discreet Packaging/5 (3, reviews)Popular Links: Supplements · How It Works · Reviews. Cialis takes from 30 minutes to 2 hours to take effect. It can last up to 36 hours. Cialis is a PDE5 inhibitor medication approved for use for erectile dysfunction (ED) and benign prostatic.