Finally, we checked customer reviews to better understand user experiences with each platform. Side effects Side effects of oral ED medicines are often mild. Medications in this drug class work by affecting an enzyme called phosphodiesterase type 5. However, others work on a cash-pay basis and don’t partner with insurance companies. Some examples of nitrates are nitroglycerin Nitro-Dur, Nitrostat, others , isosorbide mononitrate Monoket and isosorbide dinitrate Bidil. By doing so—combined with sexual stimulation—a cascade of events occurs that increases nitric oxide. · Tadalafil is used to treat men who have erectile dysfunction (also called sexual impotence). Tadalafil belongs to a group of medicines called phosphodiesterase 5 (PDE5) inhibitors. These medicines prevent an enzyme called phosphodiesterase type-5 from working too quickly. The penis is one of the areas where this enzyme works. Note: Some pharmacies do not allow the savings card to be used for opioid drugs. How much does tadalafil or cialis cost near you? Find the best tadalafil or cialis prices near you now with our cost comparison tool and start saving today. Here are answers to some frequently asked questions about drug cost and Cialis. What’s the cost per pill of Cialis 20 mg? How does this compare with the cost of other strengths ( mg, 5 mg,