The starting dose we generally recommend is the 10mg pill. The mechanism of action for ED pills is simple: They inhibit the PDE5 enzyme which regulates the signals responsible for the smooth muscle tissue. This allows the smooth muscles in the penis to relax and fill with blood. These drugs also have to be specially labeled, so many online pharmacy companies have already elected not to deliver them. It’s available in 50 mg, mg, and mg tablets.tadalafil. erectile dysfunction (ED) benign prostatic hyperplasia, or BPH). Tadalafil (Cialis) is available both as brand-name and generic tablets. Common side effects of this medication include headache and indigestion. Tadalafil (Cialis) does interact with . Get Cialis and Tadalafil pill online. Try the generic Cialis option for a fraction of the cost, after speaking with one of our online medical professionals. We have a problem!