Cost-effective: Online platforms often offer competitive prices, discounts, and deals which can lead to significant savings. Medications, including Cialis, are now available online, making it convenient for patients to access them. The effect of Cialis Professional lasts longer and these tablets should be held under the tongue. Tadalafil can be synthesized starting from D – tryptophan methyl ester and piperonal via a Pictet—Spengler reaction. Some common side effects include headaches, back pain, nasal congestion, or flushing. Follow your doctor’s directions carefully, and ask your doctor or pharmacist to explain any part you do not understand.Tadalafil (Cialis) is used to treat erectile dysfunction (ED, impotence; inability to get or keep an erection), and the symptoms of benign prostatic hyperplasia (BPH; an enlarged prostate) which include difficulty urinating (hesitation, dribbling, weak stream, and incomplete bladder emptying), painful urination, and urinary frequency and urgency in adult men. Tadalafil (Cialis) is a phosphodiesterase-5 enzyme (PDE-5) inhibitor. It works by blocking PDE This is a protein in your body that breaks down the molecules that normally cause an erection. When it blocks PDE-5, tadalafil (Cialis) helps an erection occur by allowing certain muscles in the penis to relax and the penis to fill with blood. Cialis comes in several different strengths, including: milligrams (mg) 5 mg. 10 mg. 20 mg. The cost for these different strengths depends on whether you have insurance, your individual plan.