Efficacy of sildenafil citrate Viagra in men with premature ejaculation. It should also be noted that not all SSRIs are safe to use in patients with cardiac disorders and should not be used as a treatment for cardiac concerns alone. Efficacy and safety of tramadol for premature ejaculation: a systematic review and meta-analysis. Apart from a number of behavioral approaches, the treatment of PE consists of primarily off-label use of oral selective serotonin reuptake inhibitors SSRIs via either on-demand or daily delivery. Giuliano FA. · The doctor put him on Paxil, the trade name for an SSRI called paroxetine and, over the course of the following months, Monaghan went from lasting 30 seconds to more than ten minutes. Patrick Jern. AdSwitch your scripts with ease & save big on select prescriptions. Restrictions apply. Walmart pharmacies make managing your prescriptions easy & affordable. Restrictions test1.rues: Curbside Pickup, Free 2-Day Shipping, Grocery Delivery.  · Dapoxetine is the first member of the SSRI family to be developed specifically for the treatment of PE [Citation 81]. Its rapid absorption and elimination in the body makes it suitable for the treatment of PE, but not as an antidepressant [ Citation 82 ].