What if I am taking other drugs? Physicians should discuss with patients the potential for CIALIS to augment the blood-pressure-lowering effect of alpha-blockers and antihypertensive medications. In , Pfizer scientists discovered that sildenafil, which also inhibits the PDE5 enzyme, caused penile erection in males participating in a clinical study of a heart medicine. However, because sexual stimulation is required to initiate the local penile release of nitric oxide, tadalafil’s inhibition of PDE5 will have no effect without sexual stimulation. Tadalafil treats PAH by relaxing the blood vessels in the lungs to allow blood to flow more easily. Ask your pharmacist or doctor for a copy of the manufacturer’s information for the patient.Prices for Tadalafil (Cialis) are as low as $ with a GoodRx coupon. See coupons. What are the side effects of Tadalafil (Cialis)? In clinical studies, people who took the 20 mg dose of tadalafil (Cialis) experienced an average drop in blood pressure by about 2 mm Hg. Most people won’t experience any noticeable symptoms from this . AdIt’s super shopping time. Don’t miss out. It’s super shopping time. Don’t miss out on special Black Friday offer!test1.ru has been visited by K+ users in the past month. Extra 15% off $30 sitewide with code SAVE15; Clip your mystery deal! BOGO 50% off select Walgreens health & wellness.